武大主页
武大邮箱
信息门户
English化学与生命健康交叉研究中心
孔望清
教授，博士生导师
课题组主页：http://wqkong.whu.edu.cn
研究方向
1）金属有机化学：过渡金属不对称催化
2）自由基化学：发展新的策略实现自由基反应的立体选择性控制
3）开展具有生物活性天然产物和药物分子的高效合成研究
教育与研究经历
2017.04-至今 开云体育苹果版高等研究院，教授
2014.10-2017.03 瑞士洛桑联邦理工大学 (EPFL)，博士后，导师： Jieping Zhu
2011.09-2014.09 瑞士苏黎世大学 (UZH)，博士后，导师： Cristina Nevado
2006.09-2011.06 浙江大学，博士，导师：麻生明教授（中国科学院院士）
荣誉与奖励
诺华制药博士后奖学金（2012）
苏黎世大学博士后基金（2011）
浙江省优秀毕业生（2011）
宝钢优秀学生奖（2009）
Publications
22.Kuai Wang, Zhengtian Ding, Zhijun Zhou, andWangqing Kong*.Ni-Catalyzed Enantioselective Reductive Diarylation of Activated Alkenes by Domino Cyclization/Cross-Coupling.J. Am. Chem. Soc.,2018,140, 12364-12368.
21. Yuanyuan Ping, Yuxiu Li, Jieping Zhu*,Wangqing Kong*. Construction of Quaternary Stereocenters by Palladium‐Catalyzed Carbopalladation‐Initiated Cascade Reactions.Angew. Chem. Int. Ed.2018, DOI: 10.1002/anie.201806088.
20. Yuxiu Li, Kuai Wang, Yuanyuan Ping, Yifan Wang, andWangqing Kong*.Nickel-Catalyzed Domino Heck Cyclization/Suzuki Coupling for the Synthesis of 3,3-Disubstituted Oxindoles.Org. Lett.2018,20, 921−924(Highlighted bySynfacts,2018,14(4), 410)
19. Kuai Wang,Wangqing Kong*. Recent Advances in Transition Metal Catalyzed Asymmetric Radical Reactions.Chin. J. Chem.2018,36, 247-256.(Cover Story)
Before independent work:
18.Wangqing Kong,Qian Wang, Jieping Zhu*.Water as hydride source in palladium-catalyzed enantioselective reductive Heck reaction.Angew. Chem. Int. Ed.2017,56,3987-3991. (Chosen by the Editorsas a “Hot Paper”)(Highlighted bySynfacts,2017,13(5), 495)(Highly Cited Paper)
17.Wangqing Kong, Qian Wang, Jieping Zhu*.Switchable synthesis of diversely functionalized oxindoles enabled by migratory insertion of isocyanide to a transientσ-alkylpalladium(II) complex.Angew. Chem. Int. Ed.2016,55, 9714-9718.
16.Wangqing Kong, Qian Wang, Jieping Zhu*.Palladium-catalyzed enantioselective domino heck/intermolecular C-H bond functionalization: Development and application to the synthesis of (+)-esermethole.J. Am. Chem. Soc.2015,137, 16028-16031. (Highlighted bySynfacts,2016, 12(3), 274.)
15.Wangqing Kong, Noelia Fuentes, Andres García-Domínguez, Estíbaliz Merino, Cristina Nevado*. Stereoselective synthesis of highly functionalized indanes and dibenzocycloheptadienes via complex radical cascades.Angew. Chem. Int. Ed.2015,54, 2487-2491.
14. Noelia Fuentes,Wangqing Kong, Luis Fernández-Sánchez, Estíbaliz Merino, CristinaNevado*.Cyclization cascades viaN-amidyl radicals toward highly functionalized heterocyclic scaffolds.J. Am. Chem. Soc.2015,137, 964-973.(Highly Cited Paper)
13.Wangqing Kong, Estíbaliz Merino, Cristina Nevado*. Arylphosphonylation and arylazidationof activated alkenes.Angew. Chem. Int. Ed.2014,53, 5078-5082.(Chosen by the Editors as a“Hot Paper”) (Highly Cited Paper)
12.Wangqing Kong, Estíbaliz Merino, Cristina Nevado*. Divergent reaction mechanism in the aminofluorination of alkenes.CHIMIA International Journal for Chemistry,2014,68, 430-435.
11.Wangqing Kong, Maria Casimiro, Noelia Fuentes, Estíbaliz Merino, Cristina Nevado*.Metal-freearyltrifluoromethylation ofactivated alkenes.Angew. Chem. Int. Ed. 2013,52,13086-13090.(Highly Cited Paper)
10.Wangqing Kong, Maria Casimiro, Estibaliz Merino, Cristina Nevado*. Copper-catalyzed 1-pot trifluoromethylation/arylmigration/desulfonylation and Csp2-Nbond formation of conjugated tosyl amides.J. Am. Chem. Soc.2013,135, 14480-14483.(Highly Cited Paper)
9.Wangqing Kong,Pascal Feige, Teresa de Haro, Cristina Nevado*.Regio- and enantioselective aminofluorination of alkenes.Angew. Chem. Int. Ed.2013,52, 2469-2473.(Highlighted bySynfacts2013,9 (4), 371andOrganic Chemistry Portal2014,March17.)(Highly Cited Paper)
8.Wangqing Kong, Youai Qiu,Xue Zhang, Chunling Fu,Shengming Ma*.Exclusive 1,2-aryl shift inPlatinum(II) chloride-catalyzed cyclization of 1-(indol-2-yl)-2,3-allenols.Adv. Synth. Catal.2012, 354, 2339-2347.
7.Wangqing Kong, Chunling Fu, Shengming Ma*. Efficient synthesis of carbazoles via PtCl2-catalyzed RT cyclization of 1-(indol-2-yl)-2,3-allenols: scope and mechanism.Org. Biomol. Chem.2012,10, 2164-2173.
6.Wangqing Kong, Chunling Fu, Shengming Ma*.General Au-catalyzed benzannulation towards naturally occurring carbazole alkaloids from methoxypropadiene.Chem. Eur. J.2011,17, 13134-13137.
5.Wangqing Kong, Binjie Guo, Chunling Fu, Shengming Ma*.An efficient approach to 2-bromoalken-3-ols by regioselective bromohydroxylation reaction of simple allenes with NBS.Eur. J. Org. Chem.2011, 2278-2285.
4.Wangqing Kong, Chunling Fu, Shengming Ma*.An efficient synthesis of polysubstituted naphthalene derivatives by gold-catalyzed cyclization of 1-arylalka-2,3-dienyl acetates.Eur.J.Org.Chem.2010,6545-6555.(Cover Story)
3.Wangqing Kong, Jie Cui, Yihua Yu, Guofei Chen, Chunling Fu, Shengming Ma*. PtCl4-catalyzed cyclization reaction ofβ-allenols in the presence of indole.Org.Lett.2009,11, 1213-1216.
2.Wangqing Kong, Chunling Fu, Shengming Ma*. An efficient synthesis of carbazoles from PtCl2-catalyzed cyclization of 1-(indol-2-yl)-2,3-allenols.Chem.Commun.2009, 4572–4574.
1.Wangqing Kong, Chunling Fu, Shengming Ma*.Indium and zinc-mediated Barbier-type addition reaction of 2,3-allenals with allyl bromide: an efficient synthesis of 1,5,6-alkatrien-4-ols.Org.Biomol.Chem.2008,6, 4587–4592.
专利
1.一种合成咔唑类化合物的方法，专利号：ZL 200910099482.X
2.一种合成咔唑类生物碱Siamenol的方法，专利号：ZL 201110283659.9
3.一种合成天然咔唑类生物碱的制备方法，专利号：ZL 201110283147.2
4.一种合成咔唑类化合物的方法，专利号：ZL 201210516430.X
课题组招贤纳才
博士后
薪酬待遇：工资及福利待遇根据开云体育苹果版相关规定从优考虑（五险一金，解决户口和子女入学等问题）；并根据工作业绩额外发放津贴（预计年薪25-30万元，具体薪资待遇面议）；可作为负责人申请博后基金、国家青年基金、和湖北省相关基金。博士后期间特别优秀者可协助申请开云体育苹果版正式教师（非独立成组）。
职位要求：
1）有机化学博士，有写作和发表英文科技论文经历。
2）有团队精神，工作踏实，有责任感，易沟通。
3）有金属有机化学（特别是过渡金属不对称催化）或自由基化学研究经历者优先考虑。
请发送个人简历、主要研究成果等相关资料到：wqkong@whu.edu.cn
研究助理2-3名
薪酬待遇：将提供具有竞争力的薪酬待遇，并根据工作业绩额外发放津贴，可优先报考硕士或者博士研究生。
职位要求：
1）本科或硕士学位，化学相关专业，熟悉常规有机化学实验技术和操作。
2）工作踏实，有责任感，具有良好的沟通能力和合作精神。
3）英语良好，能独立阅读英文文献。
请发送个人简历及其他能证明本人能力的相关资料到：wqkong@whu.edu.cn
研究生
欢迎全国的优秀学子报考本小组的博士或硕士研究生。要求专业基础扎实，工作踏实，有团队精神，具有良好的沟通能力。我们将提供具有竞争力的待遇，并根据工作业绩额外发放津贴。有意者请直接邮件联系wqkong@whu.edu.cn